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  1. Semantic features of 'stepped' versus 'continuous' contours in German intonation
    Autor*in: Dombrowski, Ernst
    Erschienen: 2013

  2. Discontinuation of initial antiretroviral therapy in clinical practice: Moving toward individualized therapy
    Autor*in: Di Biagio, Antonio ; Cozzi Lepri, Alessandro ; Prinapori, Roberta ; Angarano, Gioacchino ; Gori, Andrea ; Quirino, Tiziana ; De Luca, Andrea ; Costantini, Andrea ; Mussini, Cristina ; Rizzardini, Giuliano ; Castagna, Antonella ; Antinori, Andrea ; Monforte, Antonella D'arminio ; Moroni, M. ; Andreoni, M. ; Angarano, G. ; Antinori, A. ; D'Arminio Monforte, A. ; Castelli, F. ; Cauda, R. ; Di Perri, G. ; Galli, M. ; Iardino, R. ; Ippolito, G. ; Lazzarin, A. ; Perno, C. F. ; Von Schloesser, F. ; Viale, P. ; Castagna, A. ; Ceccherini Silberstein, F. ; Cozzi Lepri, A. ; Girardi, E. ; Lo Caputo, S. ; Mussini, C. ; Puoti, M. ; Ammassari, A. ; Balotta, C. ; Bandera, A. ; Bonfanti, P. ; Bonora, S. ; Borderi, M. ; Calcagno, A. ; Calza, L. ; Capobianchi, M. R.
    Erschienen: 2016

  3. Prognostic Value of the Fibrosis-4 Index in Human Immunodeficiency Virus Type-1 Infected Patients Initiating Antiretroviral Therapy with or without Hepatitis C Virus
    Autor*in: Mussini, Cristina ; Lorenzini, Patrizia ; Puoti, Massimo ; Lichtner, Miriam ; Lapadula, Giuseppe ; Di Giambenedetto, Simona ; Antinori, Andrea ; Madeddu, Giordano ; Cozzi Lepri, Alessandro ; D'Arminio Monforte, Antonella ; De Luca, Andrea ; Moroni, M. ; Angarano, G. ; Antinori, A. ; D'Arminio Monforte, A. ; Castelli, F. ; Cauda, R. ; Di Perri, G. ; Galli, M. ; Iardino, R. ; Ippolito, G. ; Lazzarin, A. ; Perno, C. F. ; Von Schloesser, F. ; Viale, P. ; Castagna, A. ; Ceccherini Silberstein, F. ; Cozzi Lepri, A. ; Girardi, E. ; Lo Caputo, S. ; Mussini, C. ; Puoti, M. ; Andreoni, M. ; Ammassari, A. ; Balotta, C. ; Bandera, A. ; Bonora, S. ; Borderi, M. ; Calcagno, A. ; Calza, L. ; Capobianchi, M. R. ; Cingolani, A. ; Cinque, P.
    Erschienen: 2015

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  4. Ultrasonographic evaluation of urethrovesical junction mobility: correlation with type of delivery and stress urinary incontinence
    Autor*in: Cosimato, Cosimo ; Cipullo, Lucio M. A. ; Troisi, Jacopo ; DI SPIEZIO SARDO, ATTILIO ; Tommaselli, Giovanni Antonio ; Oro, Rosa Rita ; Zullo, Fulvio ; Altieri, Vincenzo
    Erschienen: 2015

    A relationship between urinary incontinence and hypermobility of the urethrovesical junction (UVJ) during pregnancy has been described. The aim of the study was to compare the effects of vaginal delivery (VD) and caesarean section (CS) on UVJ... mehr

     

    A relationship between urinary incontinence and hypermobility of the urethrovesical junction (UVJ) during pregnancy has been described. The aim of the study was to compare the effects of vaginal delivery (VD) and caesarean section (CS) on UVJ mobility. The retrovesical angle (RVA) and the anterior angle between the UVJ and the pubic bone, the pubovesical angle (PVA), were evaluated ultrasonographically in controls and pregnant women during their first pregnancy between 38 and 40 weeks, and then re-evaluated 6 weeks and 6 months after delivery. All patients completed a validated questionnaire (ICIQ-SF). Differences between and within groups were assessed with Student's t test, the chi-squared test for trend, and one-way two-tailed analysis of variance with Scheff,'s post-hoc test. The correlation between PVA and RVA was evaluated using the Spearman R correlation. The positive predictive value, negative predictive value, sensitivity and specificity for the prediction of stress urinary incontinence (SUI) symptoms were also determined. Included in the study were 42 controls and 217 pregnant women. PVA at rest, during cough and Valsalva manoeuvre was significantly higher in pregnant women than in controls and in women 6 weeks after VD in comparison with women who had undergone CS. Patients affected by SUI showed a significantly higher PVA. RVA did not differ between subjects affected or not by SUI symptoms. PVA and RVA were not correlated with each other. PVA and RVA are increased in pregnant women in comparison with controls. In patients undergoing VD, PVA is restored significantly later than in those undergoing CS. The change in RVA after pregnancy and delivery seems to persist longer than the change in PVA.

     
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  5. Oleic acid content of a meal promotes oleoylethanolamide response and reduces subsequent energy intake in humans
    Autor*in: MENNELLA, ILARIO ; SAVARESE, MARIA ; FERRACANE, ROSALIA ; SACCHI, RAFFAELE ; VITAGLIONE, PAOLA
    Erschienen: 2015

    Animal data suggest that dietary fat composition may influence endocannabinoid (EC) response and dietary behavior. This study tested the hypothesis that fatty acid composition of a meal can influence the short-term response of ECs and subsequent... mehr

     

    Animal data suggest that dietary fat composition may influence endocannabinoid (EC) response and dietary behavior. This study tested the hypothesis that fatty acid composition of a meal can influence the short-term response of ECs and subsequent energy intake in humans. Fifteen volunteers on three occasions were randomly offered a meal containing 30 g of bread and 30 mL of one of three selected oils: sunflower oil (SO), high oleic sunflower oil (HOSO) and virgin olive oil (VOO). Plasma EC concentrations and appetite ratings over 2 h and energy intake over 24 h following the experimental meal were measured. Results showed that after HOSO and VOO consumption the circulating oleoylethanolamide (OEA) was significantly higher than after SO consumption; a concomitantly significant reduction of energy intake was found. For the first time the oleic acid content of a meal was demonstrated to increase the post-prandial response of circulating OEA and to reduce energy intake at subsequent meals in humans.

     
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  6. Adipose tissue transcriptome reflects variations between subjects with continued weight loss and subjects regaining weight 6 mo after caloric restriction independent of energy intake.
    Autor*in: Márquez-Quiñones, Adriana ; Mutch, David, ; Debard, Cyrille ; Wang, Ping ; Combes, Marion ; Roussel, Balbine ; Holst, Claus ; Martinez, J Alfredo ; Handjieva-Darlenska, Teodora ; Kalouskova, Pavla ; Jebb, Susan ; Babalis, Dimitris ; Pfeiffer, Andreas, ; Larsen, Thomas, ; Astrup, Arne ; Saris, Wim, ; Mariman, Edwin ; Clément, Karine ; Vidal, Hubert ; Langin, Dominique ; Viguerie, Nathalie
    Erschienen: 2010
    Verlag:  HAL CCSD ; Oxford University Press

    International audience ; BACKGROUND: The mechanisms underlying body weight evolution after diet-induced weight loss are poorly understood. OBJECTIVE: We aimed to identify and characterize differences in the subcutaneous adipose tissue (SAT)... mehr

     

    International audience ; BACKGROUND: The mechanisms underlying body weight evolution after diet-induced weight loss are poorly understood. OBJECTIVE: We aimed to identify and characterize differences in the subcutaneous adipose tissue (SAT) transcriptome of subjects with different weight changes after energy restriction-induced weight loss during 6 mo on 4 different diets. DESIGN: After an 8-wk low-calorie diet (800 kcal/d), we randomly assigned weight-reduced obese subjects from 8 European countries to receive 4 diets that differed in protein and glycemic index content. In addition to anthropometric and plasma markers, SAT biopsies were taken at the beginning [clinical investigation day (CID) 2] and end (CID3) of the weight follow-up period. Microarray analysis was used to define SAT gene expression profiles at CID2 and CID3 in 22 women with continued weight loss (successful group) and in 22 women with weight regain (unsuccessful group) across the 4 dietary arms. RESULTS: Differences in SAT gene expression patterns between successful and unsuccessful groups were mainly due to weight variations rather than to differences in dietary macronutrient content. An analysis of covariance with total energy intake as a covariate identified 1338 differentially expressed genes. Cellular growth and proliferation, cell death, cellular function, and maintenance were the main biological processes represented in SAT from subjects who regained weight. Mitochondrial oxidative phosphorylation was the major pattern associated with continued weight loss. CONCLUSIONS: The ability to control body weight loss independent of energy intake or diet composition is reflected in the SAT transcriptome. Although cell proliferation may be detrimental, a greater mitochondrial energy gene expression is suggested as being beneficial for weight control. This trial was registered at clinicaltrials.gov as NCT00390637.

     
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